Background: Gastroesophageal reflux disease (GERD), which leads to acid reflux into the esophagus, is a common\ngastrointestinal disorder. Several studies have shown the prevalence of GERD in Iranian population, but their\nevidence is contradictory. Therefore, the present study was conducted to investigate the epidemiology of GERD in\nIran.\nMethods: The entire steps of this systematic review and meta-analysis were based on the MOOSE protocol, and\nthe results were reported accordance with the PRISMA guideline. This review is registered on PROSPERO\n(registration number: CRD42020142861). To find potentially relevant published articles, comprehensive search was\ndone on international online databases Scopus, Science Direct, EMBASE, PubMed/Medline, CINAHL, EBSCO,....................................
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